Felix Hoffmann was born on 21 January 1868 in Ludwigsburg. In 1889 he began to study chemistry at Ludwig-Maximilians-University of Munich to study pharmacy and ended in 1890 with a state pharmacy exam. In 1891 he graduated magna cum laude from the University of Munich. Two years later he received his doctorate, as well as magna cum laude, after completing his thesis entitled "On certain derivatives dihydroanthracene." In 1894, he joined Bayer as a chemist .
In 1894, he joined Bayer as a chemist.
Hoffman tries to find alternative ways of treating arthritis without using sodium
salicylate, sodium salicylate used to treat arthritis often attacks the lining of the stomach and causes sufferers of considerable illness due to irritation. Because of the acidity of making hard salicylates in the stomach, he begins to look for acid formations that cause him to synthesize acetylsalicylic acid, a compound that shares other therapeutic properties of salicylates but lacks strong acidity that causes gastric irritation.
So by acetylating salicylic acid with acetic acid, he succeeded in creating acetylsalicylic acid (ASA) in pure and stable chemical form.
On August 10, 1897, Hoffmann successfully synthesized acetylsalicylic acid (ASA) for the first time in a stable form that could be used for medical applications
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A : Gugus asetil
spir : nama bunga tersebut dalam bahasa Latin
spiraea : suku kata tambahan yang sering kali digunakan
in : untuk zat pada masa tersebut
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In the 20th century, salicylic acid began to be used as a treatment for skin conditions like acne, psoriasis, warts, and calluses.