| Measurement | System | Route/Organism | Dose | Effect | Date |
|---|---|---|---|---|---|
| Mutation Data | mutation in microorganisms | /Escherichia coli | 1 µmol/L (-enzymatic activation step) | March 2014 | |
| Reproductive Effects | inhalation/rat | 5000 ppm/6H (6-19D pregnant) | Reproductive: Effects on embryo or fetus: Fetotoxicity (except death, e.g., stunted fetus) | March 2014 | |
| Reproductive Effects | oral/mouse | 2592 mg/kg (6-17D pregnant) | Reproductive: Effects on fertility: Litter size (e.g., # fetuses per litter;measured before birth) Reproductive: Effects on embryo or fetus: Fetotoxicity (except death, e.g., stunted fetus) | March 2014 | |
| Tumorigenic Data | inhalation/mouse | lowest published toxic concentration: 1800 ppm/6H/2Y- intermittent | Tumorigenic: Carcinogenic by RTECS criteria Liver: Tumors | March 2014 | |
| Acute Toxicity Data | oral/guinea pig | lethal dose (50 percent kill): 2300 mg/kg | March 2014 | ||
| Other Multiple Dose Data | inhalation/mouse | lowest published toxic concentration: 200 ppm/6H/14W- intermittent | Liver: Changes in liver weight | March 2014 | |
| Other Multiple Dose Data | inhalation/mouse | lowest published toxic concentration: 15000 mg/m3/5D- intermittent/td> | Liver: Other changes Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Hepatic microsomal mixed oxidase (dealkylation, hydroxylation, etc.) | March 2014 | |
| Other Multiple Dose Data | inhalation/mouse | lowest published toxic concentration: 8 gm/m3/2H/60D- intermittent | Lung, Thorax, or Respiration: Other changes Related to Chronic Data: Death in the "MULTIPLE DOSE" data type field | March 2014 | |
| Acute Toxicity Data | inhalation/rat | lethal concentration (50 percent kill): 21000 ppm/3H | Behavioral: Sleep Lung, Thorax, or Respiration: Respiratory stimulation Gastrointestinal: Nausea or vomiting | March 2014 | |
| Other Multiple Dose Data | inhalation/rat | lowest published toxic concentration: 1.5 gm/m3/61D- intermittent | Blood: Changes in leukocyte (WBC) count | March 2014 |